Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823326 | 0.82 | EPHX2 (0.40) | JUNNFKB1NFKB2RELADHODH | |
| SCHEMBL11835366 | 0.82 | DHODH (0.40) | DHODHEPHX2MEN1KMT2AKDM4E | |
| SCHEMBL11824162 | 0.81 | MAPT (0.52) | MEN1KMT2AGAAMAPTRAB9A | |
| SCHEMBL23337972 | 0.79 | TRPV1 (0.42) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL11821391 | 0.78 | ALDH1A1 (0.52) | NFKB1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1013642 | 0.75 | CASP1 (0.47) | KDM4EALDH1A1CASP1 | |
| SCHEMBL11827092 | 0.74 | NPC1 (0.44) | NFKB1NFKB2RELAKMT2AALDH1A1 | |
| SCHEMBL11823559 | 0.74 | MAPT (0.50) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL6479400 | 0.74 | KCNQ3 (0.41) | DHODHEPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL23338555 | 0.74 | TDP1 (0.48) | ALDH1A1GAAMAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |