Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821391 | 0.85 | ALDH1A1 (0.52) | MAPTTDP1LMNAEGFRCYP1A2 | |
| SCHEMBL11823559 | 0.81 | MAPT (0.50) | MAPTTDP1LMNAMEN1KMT2A | |
| SCHEMBL11827092 | 0.81 | NPC1 (0.44) | MAPTLMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11819244 | 0.81 | JUN (0.41) | MAPTTDP1MEN1KMT2ARAB9A | |
| SCHEMBL23338555 | 0.81 | TDP1 (0.48) | MAPTTDP1LMNARAB9AGAA | |
| SCHEMBL11818693 | 0.79 | MAPT (0.46) | MAPTLMNAMPICYP1A2CYP3A4 | |
| SCHEMBL11822532 | 0.79 | MAPT (0.46) | MAPTLMNAEGFRERBB3CYP1A2 | |
| SCHEMBL4867807 | 0.69 | AHR (0.42) | MAPTTDP1CYP1A2KMT2APTGS2 | |
| SCHEMBL24176367 | 0.69 | MEN1 (0.56) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL24176483 | 0.69 | POLB (0.51) | MAPTTDP1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |