Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818693 | 0.83 | MAPT (0.46) | AGPAT2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11819244 | 0.82 | JUN (0.41) | DHODHAGPAT2MEN1KMT2AKDM4E | |
| SCHEMBL11833599 | 0.81 | MAPT (0.40) | AGPAT2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11833640 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL5918466 | 0.79 | CASP1 (0.45) | AGPAT2ALDH1A1GAAMAPTCASP1 | |
| SCHEMBL11826546 | 0.77 | MAPT (0.53) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL11823326 | 0.74 | EPHX2 (0.40) | DHODHAGPAT2MEN1KMT2AKDM4E | |
| SCHEMBL11823603 | 0.74 | DHODH (0.42) | DHODHAGPAT2MEN1KMT2AABL1 | |
| SCHEMBL10265141 | 0.70 | ALDH1A1 (0.39) | KDM4EALDH1A1GAAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1205235 | 0.68 | ALDH1A1 (0.38) | KDM4EALDH1A1GAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |