Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | PTPRG | P23470 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818479 | 0.88 | CA2 (0.46) | MEN1KMT2AALDH1A1CA2CA4 | |
| SCHEMBL11818248 | 0.86 | CA2 (0.43) | CYP1A2TAS2R14PTGDR2MEN1KMT2A | |
| SCHEMBL11820018 | 0.85 | CA2 (0.53) | CYP1A2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11821491 | 0.84 | MEN1 (0.45) | CYP1A2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11825522 | 0.83 | ALDH1A1 (0.46) | CYP1A2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11819449 | 0.82 | CYP1A2 (0.48) | CYP1A2APEX1RAB9APTGDR2MEN1 | |
| SCHEMBL11816465 | 0.81 | KDM5A (0.41) | CA2CA4EPAS1PTPRG | |
| SCHEMBL11817917 | 0.78 | PTPRG (0.47) | RAB9AMEN1KMT2AHPGDCA2 | |
| SCHEMBL11814899 | 0.78 | PPARD (0.43) | CA2CA4EPAS1PTPRG | |
| SCHEMBL11817140 | 0.78 | CA2 (0.42) | MEN1KMT2AALDH1A1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |