Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822961 | 0.88 | ALDH1A1 (0.49) | NPC1RAB9ATNFNOD1MEN1 | |
| SCHEMBL11819309 | 0.87 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL11816193 | 0.86 | KMT2A (0.44) | RAB9AMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL11827713 | 0.85 | KMT2A (0.43) | RAB9AMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL11822223 | 0.83 | MEN1 (0.46) | NPC1RAB9ATNFNOD1MEN1 | |
| SCHEMBL11814493 | 0.81 | ALDH1A1 (0.49) | NPC1RAB9ATNFNOD1MEN1 | |
| SCHEMBL11819833 | 0.81 | KMT2A (0.52) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11853927 | 0.78 | TRPV4 (0.45) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11820863 | 0.78 | KMT2A (0.48) | NPC1RAB9ATNFNOD1MEN1 | |
| SCHEMBL11819988 | 0.75 | LMNA (0.46) | MEN1KMT2AALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |