Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819988 | 0.90 | LMNA (0.46) | ALDH1A1LMNAKMT2AMEN1MCL1 | |
| SCHEMBL11820801 | 0.87 | NPC1 (0.45) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL11816193 | 0.82 | KMT2A (0.44) | KMT2AMEN1HTTMAPT | |
| SCHEMBL11827713 | 0.81 | KMT2A (0.43) | KMT2AMEN1HTT | |
| SCHEMBL11819833 | 0.79 | KMT2A (0.52) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL11822961 | 0.77 | ALDH1A1 (0.49) | ALDH1A1LMNAKMT2AMEN1MCL1 | |
| SCHEMBL11816930 | 0.76 | TAS2R14 (0.59) | KMT2AMEN1 | |
| SCHEMBL11815605 | 0.73 | CA12 (0.46) | ALDH1A1KMT2AMEN1MAPTMCL1 | |
| SCHEMBL11822223 | 0.71 | MEN1 (0.46) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL11823334 | 0.70 | MCL1 (0.44) | ALDH1A1LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |