Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | PTPRG | P23470 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820489 | 1.00 | PTPRC (0.46) | PTPRCPTPRGTAS2R14VCAM1AR | |
| SCHEMBL11826205 | 0.96 | PTPRC (0.47) | PTPRCPTPRGTAS2R14VCAM1AR | |
| SCHEMBL11822163 | 0.90 | CA2 (0.47) | TAS2R14VCAM1CA12CA1CA9 | |
| SCHEMBL11818580 | 0.90 | CA2 (0.47) | TAS2R14VCAM1CA12CA1CA9 | |
| SCHEMBL11819921 | 0.89 | CNR2 (0.48) | TAS2R14VCAM1CA12CA9CNR2 | |
| SCHEMBL11821805 | 0.89 | KMT2A (0.45) | PTPRCPTPRGVCAM1CA12CA1 | |
| SCHEMBL11825369 | 0.89 | KMT2A (0.45) | PTPRCPTPRGVCAM1CA12CA1 | |
| SCHEMBL11815898 | 0.86 | PTPRG (0.46) | PTPRCPTPRGTAS2R14VCAM1AR | |
| SCHEMBL11820805 | 0.86 | CA2 (0.48) | TAS2R14VCAM1CA12CA1CA9 | |
| SCHEMBL11817894 | 0.85 | TAS2R14 (0.47) | TAS2R14VCAM1CA12CA9CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |