Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11825369 | 1.00 | KMT2A (0.45) | KMT2AMEN1HTTS1PR3ALDH1A1 | |
| SCHEMBL11819918 | 0.96 | KMT2A (0.47) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL11818861 | 0.92 | KMT2A (0.45) | KMT2AMEN1HTTS1PR3ALDH1A1 | |
| SCHEMBL11822163 | 0.90 | CA2 (0.47) | KMT2AMEN1S1PR3ALDH1A1MAPT | |
| SCHEMBL11818580 | 0.90 | CA2 (0.47) | KMT2AMEN1S1PR3ALDH1A1MAPT | |
| SCHEMBL11819921 | 0.89 | CNR2 (0.48) | KMT2AMEN1ALDH1A1MAPTCNR2 | |
| SCHEMBL11820442 | 0.89 | PTPRC (0.46) | KMT2AS1PR3CNR2VCAM1CA2 | |
| SCHEMBL11820489 | 0.89 | PTPRC (0.46) | KMT2AS1PR3CNR2VCAM1CA2 | |
| SCHEMBL11825334 | 0.86 | KMT2A (0.43) | KMT2AMEN1HTTALDH1A1VCAM1 | |
| SCHEMBL11820805 | 0.86 | CA2 (0.48) | KMT2AMEN1ALDH1A1MAPTVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |