Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818580 | 0.96 | CA2 (0.47) | CA2CA4RXFP1ALDH1A1MAPT | |
| SCHEMBL11822163 | 0.96 | CA2 (0.47) | CA2CA4RXFP1ALDH1A1MAPT | |
| SCHEMBL11817894 | 0.91 | TAS2R14 (0.47) | CA2CA4RXFP1ALDH1A1MAPT | |
| SCHEMBL11819726 | 0.90 | LMNA (0.45) | CA2CA4ALDH1A1MAPTKMT2A | |
| SCHEMBL11823574 | 0.90 | MAPT (0.44) | CA2CA4RXFP1ALDH1A1MAPT | |
| SCHEMBL11826205 | 0.90 | PTPRC (0.47) | CA2CA4RXFP1ALDH1A1MAPT | |
| SCHEMBL11819918 | 0.90 | KMT2A (0.47) | CA2CA4RXFP1ALDH1A1MAPT | |
| SCHEMBL11819669 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11821357 | 0.87 | CNR2 (0.48) | CA2CA4ALDH1A1MAPTTP53 | |
| SCHEMBL11821631 | 0.87 | CA2 (0.49) | CA2CA4ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |