Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 11/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816991 | 0.86 | MRGPRX4 (0.46) | MEP1BTRPM8WDR5PPARAMRGPRX4 | |
| SCHEMBL11818965 | 0.85 | PPARA (0.39) | MEP1BTRPM8WDR5PPARAMRGPRX4 | |
| SCHEMBL11826737 | 0.80 | PTPRZ1 (0.33) | PTPRZ1 | |
| SCHEMBL11818392 | 0.79 | TSHR (0.43) | MEP1BPTPRZ1TRPM8WDR5PPARA | |
| SCHEMBL11819247 | 0.77 | MMP1 (0.41) | MMP2MMP9 | |
| SCHEMBL11818108 | 0.77 | PTPRZ1 (0.40) | MEP1BPTPRZ1TRPM8WDR5PPARA | |
| SCHEMBL24017232 | 0.76 | AURKA (0.44) | MEP1BTRPM8WDR5PPARAMRGPRX4 | |
| SCHEMBL11819044 | 0.73 | KMT2A (0.38) | MEP1BMRGPRX4MMP2MMP9 | |
| SCHEMBL22926044 | 0.73 | AURKA (0.44) | WDR5PPARAMRGPRX4AURKATPX2 | |
| SCHEMBL24017233 | 0.72 | AURKA (0.43) | MEP1BWDR5PPARAMRGPRX4AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |