Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818815 | 0.88 | MRGPRX4 (0.42) | BCHEACHEMEP1BTRPM8WDR5 | |
| SCHEMBL11820243 | 0.85 | MRGPRX4 (0.48) | MEP1BPPARAMRGPRX4AURKATPX2 | |
| SCHEMBL11818392 | 0.80 | TSHR (0.43) | PTPRZ1MEP1BTRPM8WDR5MMP2 | |
| SCHEMBL11823334 | 0.79 | MCL1 (0.44) | MEN1LMNAPOLBHPGDRAB9A | |
| SCHEMBL11820784 | 0.77 | MEP1B (0.41) | PTPRZ1MEP1BTRPM8WDR5MMP2 | |
| SCHEMBL11810807 | 0.77 | ALDH1A1 (0.41) | BCHEACHEMMP2MMP9MEN1 | |
| SCHEMBL24017232 | 0.76 | AURKA (0.44) | MEP1BTRPM8WDR5CA1CA2 | |
| SCHEMBL11815385 | 0.76 | MRGPRX4 (0.46) | MEP1BPPARAMRGPRX4AURKATPX2 | |
| SCHEMBL11820227 | 0.74 | TRPV1 (0.46) | PPARAMRGPRX4AURKATPX2MEN1 | |
| SCHEMBL11817074 | 0.73 | DAO (0.41) | PPARAMRGPRX4AURKATPX2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |