Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819247 | 0.86 | MMP1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11819044 | 0.81 | KMT2A (0.38) | TAS2R14MEN1KMT2A | |
| SCHEMBL11820784 | 0.80 | MEP1B (0.41) | PTPRZ1 | |
| SCHEMBL11816782 | 0.77 | TSHR (0.43) | PTPRZ1RXRARXRBTPMTALDH1A1 | |
| SCHEMBL11820864 | 0.75 | TAS2R14 (0.44) | ALDH1A1TAS2R14KMT2A | |
| SCHEMBL11818964 | 0.73 | LCK (0.44) | TPMTALDH1A1LCKFYNMEN1 | |
| SCHEMBL18513400 | 0.71 | LCK (0.52) | TPMTALDH1A1LCKFYNMEN1 | |
| SCHEMBL732949 | 0.71 | LCK (0.57) | TPMTALDH1A1LCKFYNMEN1 | |
| SCHEMBL11816991 | 0.67 | MRGPRX4 (0.46) | RXRARXRBMEN1KMT2A | |
| SCHEMBL11819495 | 0.67 | KDM1A (0.39) | PTPRZ1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |