Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | PTPRG | P23470 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821631 | 0.90 | CA2 (0.49) | KMT2AMEN1HTTCA2CA4 | |
| SCHEMBL11815898 | 0.89 | PTPRG (0.46) | KMT2AMEN1CA2CA4PTPRG | |
| SCHEMBL11819918 | 0.88 | KMT2A (0.47) | KMT2AMEN1HTTCA2CA4 | |
| SCHEMBL11821805 | 0.86 | KMT2A (0.45) | KMT2AMEN1HTTCA2CA4 | |
| SCHEMBL11825369 | 0.86 | KMT2A (0.45) | KMT2AMEN1HTTCA2CA4 | |
| SCHEMBL11820863 | 0.85 | KMT2A (0.48) | KMT2AMEN1HTTCA2CA4 | |
| SCHEMBL11819740 | 0.83 | VCAM1 (0.40) | HTTCA2CA4PTPRGVCAM1 | |
| SCHEMBL11825881 | 0.83 | TAS2R14 (0.43) | KMT2AMEN1HTTCA2CA4 | |
| SCHEMBL11813988 | 0.82 | TAS2R14 (0.45) | KMT2AMEN1HTTVCAM1LMNA | |
| SCHEMBL11816192 | 0.81 | MAPT (0.48) | KMT2AMEN1HTTVCAM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |