Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828042 | 0.87 | GFER (0.55) | MAPTLMNAPARP1MC4RNPSR1 | |
| SCHEMBL11826994 | 0.87 | TACR1 (0.61) | MAPTLMNAPARP1MC4RKMT2A | |
| SCHEMBL11829657 | 0.83 | TACR1 (0.73) | LMNAKMT2AMEN1TACR1POLB | |
| SCHEMBL11834886 | 0.80 | GFER (0.54) | MAPTLMNAPARP1NPSR1ALDH1A1 | |
| SCHEMBL11550991 | 0.79 | TACR1 (0.52) | ALDH1A1TACR1POLB | |
| SCHEMBL11333760 | 0.79 | DRD2 (0.69) | MAPTLMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL11825414 | 0.78 | DRD2 (0.61) | MAPTPARP1ALDH1A1KMT2AKDM4E | |
| SCHEMBL30343681 | 0.77 | ALDH1A1 (0.71) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL1740428 | 0.77 | ALDH1A1 (0.71) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL11335727 | 0.76 | ESR1 (0.61) | MAPTLMNAPARP1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |