Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828042 | 0.92 | GFER (0.55) | TACR1GFERMAPTLMNAKMT2A | |
| SCHEMBL11821884 | 0.87 | MAPT (0.65) | TACR1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL11819506 | 0.86 | KMT2A (0.56) | TACR1DRD2DRD4DRD3LMNA | |
| SCHEMBL11834886 | 0.85 | GFER (0.54) | TACR1GFERMAPTLMNAKMT2A | |
| SCHEMBL11335321 | 0.82 | HTR1A (0.68) | DRD2DRD4DRD3MAPTLMNA | |
| SCHEMBL11823715 | 0.81 | SLC6A4 (0.65) | DRD2DRD4DRD3PARP1 | |
| SCHEMBL11822960 | 0.80 | TACR1 (0.69) | TACR1LMNAKMT2AMEN1 | |
| SCHEMBL11823392 | 0.78 | KMT2A (0.56) | TACR1GFERMAPTLMNAKMT2A | |
| SCHEMBL15229645 | 0.77 | APEX1 (0.59) | MAPTKMT2AMEN1 | |
| SCHEMBL11834769 | 0.77 | MEN1 (0.50) | TACR1DRD4DRD3GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |