Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828042 | 0.94 | GFER (0.55) | GFERKMT2ALMNAMAPTMEN1 | |
| SCHEMBL11826994 | 0.85 | TACR1 (0.61) | GFERKMT2ALMNAPOLBMAPT | |
| SCHEMBL11822960 | 0.83 | TACR1 (0.69) | KMT2ALMNAMEN1TACR1 | |
| SCHEMBL11823392 | 0.82 | KMT2A (0.56) | GFERKMT2ALMNAPOLBMAPT | |
| SCHEMBL11834769 | 0.81 | MEN1 (0.50) | GFERKMT2APOLBMEN1GAA | |
| SCHEMBL11825601 | 0.80 | MAPT (0.64) | KMT2ALMNAPOLBMAPTMEN1 | |
| SCHEMBL11828423 | 0.80 | HTR1A (0.52) | PARP1PARP2 | |
| SCHEMBL11821884 | 0.80 | MAPT (0.65) | KMT2ALMNAPOLBMAPTMEN1 | |
| SCHEMBL11829997 | 0.79 | PKM (0.48) | KMT2ALMNAPOLBMAPTGAA | |
| SCHEMBL11830955 | 0.78 | POLB (0.46) | KMT2APOLBALDH1A1TSHRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |