Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 14/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834615 | 0.84 | MAT2A (0.64) | MAT2ABRD4FNTAFNTBSMN1; SMN2 | |
| SCHEMBL11849955 | 0.79 | L3MBTL1 (0.50) | MAT2ASMN1; SMN2L3MBTL1MEN1POLB | |
| SCHEMBL1599263 | 0.76 | HPGD (0.41) | MAT2ABRD4FNTAFNTBSMN1; SMN2 | |
| SCHEMBL11710604 | 0.75 | KMT2A (0.46) | L3MBTL1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL5794890 | 0.72 | MAT2A (0.53) | MAT2ABRD4FNTAFNTB | |
| SCHEMBL10128829 | 0.71 | POLB (0.44) | SMN1; SMN2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL10128851 | 0.69 | POLB (0.44) | SMN1; SMN2GABRA1GABRA5GABRA2MEN1 | |
| SCHEMBL11825860 | 0.69 | MAT2A (0.48) | MAT2ABRD4FNTAFNTBSMN1; SMN2 | |
| SCHEMBL9092790 | 0.69 | GSK3B (0.49) | BRD4SMN1; SMN2GSK3B | |
| SCHEMBL11779422 | 0.68 | KDM4E (0.61) | BRD4SMN1; SMN2PBRM1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000153-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |