Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819978 | 0.85 | MAPT (0.41) | L3MBTL1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL10842650 | 0.80 | NPSR1 (0.53) | L3MBTL1MAPTF2RL3MEN1KMT2A | |
| SCHEMBL11834615 | 0.79 | MAT2A (0.64) | L3MBTL1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11822371 | 0.79 | MAT2A (0.46) | L3MBTL1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL11702410 | 0.78 | L3MBTL1 (0.58) | L3MBTL1MAPTF2RL3MEN1KMT2A | |
| SCHEMBL10841737 | 0.74 | THRB (0.61) | L3MBTL1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL30979014 | 0.70 | ABCG2 (0.52) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL981612 | 0.70 | MAPT (0.54) | L3MBTL1MAPTF2RL3MEN1KMT2A | |
| SCHEMBL10841715 | 0.70 | THRB (0.45) | L3MBTL1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL10842636 | 0.68 | POLB (0.51) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000151-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |