Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 8/20 | 0.44 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823985 | 0.88 | SMN1; SMN2 (0.45) | BRD4PDE2APDE10AKDM4EALDH1A1 | |
| SCHEMBL11826249 | 0.87 | HSD11B1 (0.47) | MAT2AFNTAFNTBBRD4PDE2A | |
| SCHEMBL11825891 | 0.87 | MAT2A (0.47) | MAT2AFNTAFNTBBRD4PDE2A | |
| SCHEMBL11834615 | 0.85 | MAT2A (0.64) | MAT2AFNTAFNTBBRD4GABRA1 | |
| SCHEMBL11826377 | 0.84 | PDE2A (0.47) | MAT2AFNTAFNTBBRD4PDE2A | |
| SCHEMBL11819978 | 0.82 | MAPT (0.41) | FNTAFNTBBRD4GABRA1GABRG2 | |
| SCHEMBL11828073 | 0.80 | FNTA (0.46) | MAT2AFNTAFNTBBRD4PDE2A | |
| SCHEMBL5794890 | 0.76 | MAT2A (0.53) | MAT2AFNTAFNTBBRD4PDE2A | |
| SCHEMBL5793173 | 0.75 | PDE2A (0.45) | PDE2APDE10AGABRA1GABRG2HTR2A | |
| SCHEMBL11822371 | 0.69 | MAT2A (0.46) | MAT2AFNTAFNTBBRD4GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000151-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-4000153-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3993660-A | 2-[3-(Phthalimidomethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenones | THE UPJOHN COMPANY (US) | 1976-11-23 | — | — | US | disclosed |