Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 18/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 5/20 | 0.40 |
| ▸ | FLT4 | P35916 | 5/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824198 | 0.83 | CYP2A6 (0.40) | KDRMAPK9MAPK10 | |
| SCHEMBL11818894 | 0.77 | TSHR (0.40) | — | |
| SCHEMBL11820624 | 0.74 | FAAH (0.40) | KDRFLT1 | |
| Oxalic Acid SCHEMBL11817609 | 0.73 | KDR (0.41) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL27659057 | 0.72 | P2RX4 (0.46) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL11816596 | 0.71 | CYP1A2 (0.43) | — | |
| SCHEMBL15315998 | 0.71 | MAPK9 (0.43) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL11821610 | 0.70 | NPC1 (0.46) | KDRFLT1 | |
| SCHEMBL9026902 | 0.70 | KDR (0.53) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL15315972 | 0.69 | MAPK10 (0.83) | KDRMAPK9MAPK10FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3961062-A | Pharmaceutical composition containing 1-(imidazole-1-yl)-isoquinolines and method of treating hyperlipemia | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | disclosed |