Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 2/20 | 0.45 |
| ▸ | PLK2 | Q9NYY3 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15746078 | 0.91 | KDR (0.49) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL28566945 | 0.88 | KDR (0.49) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL15746081 | 0.83 | L3MBTL1 (0.47) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL528245 | 0.82 | MAPK9 (0.54) | KDRMAPK9MAPK10FLT1FLT4 | |
| Benzene SCHEMBL27839441 | 0.82 | MAPK9 (0.54) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL6624109 | 0.80 | ALDH1A1 (0.44) | PLK1PLK2 | |
| SCHEMBL15746026 | 0.80 | KDR (0.41) | KDRMAPK9MAPK10FLT1FLT4 | |
| Hydrochloric Acid SCHEMBL27683877 | 0.80 | MAPK9 (0.53) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL29526693 | 0.79 | MAPK9 (0.44) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL3820141 | 0.78 | KDR (0.48) | KDRMAPK9MAPK10FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576393-B1 | Curable compositions based on epoxy resins or mixtures of epoxy resins and polyisocyanates containing a trisimidazolyltriazone | CIBA GEIGY AG (CH) | 1996-04-10 | — | — | EP | disclosed |
| US-5391681-A | Hardeners or promoters having low temperature reactivity and storage stability | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0576393-A1 | Curable compositions based on epoxy resins or mixtures of epoxy resins and polyisocyanates containing a trisimidazolyltriazone | CIBA-GEIGY AG (CH) | 1993-12-29 | — | — | EP | disclosed |