Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Theofibrate SCHEMBL3960649 | 0.74 | ADORA2B (0.60) | LMNAMAPK1ADORA2BSMN1; SMN2RXFP1 | |
| Theofibrate SCHEMBL49272 | 0.74 | ADORA2B (0.60) | LMNAMAPK1ADORA2BSMN1; SMN2RXFP1 | |
| SCHEMBL10963455 | 0.72 | LMNA (0.60) | LMNAMAPK1SMN1; SMN2RXFP1POLB | |
| SCHEMBL20561174 | 0.72 | LMNA (1.00) | LMNAMAPK1ADORA2BSMN1; SMN2RXFP1 | |
| Acefylline Clofibrol SCHEMBL2110473 | 0.72 | MAPK1 (0.61) | LMNAMAPK1ADORA2BSMN1; SMN2RXFP1 | |
| SCHEMBL18399526 | 0.71 | ADORA2B (0.68) | LMNAMAPK1ADORA2BSMN1; SMN2RXFP1 | |
| SCHEMBL11823636 | 0.71 | LMNA (0.45) | LMNAMAPK1ADORA2BSMN1; SMN2RXFP1 | |
| SCHEMBL7011108 | 0.70 | LMNA (0.84) | LMNAMAPK1ADORA2BSMN1; SMN2RXFP1 | |
| SCHEMBL16120984 | 0.70 | ADORA2B (0.81) | LMNAMAPK1ADORA2BSMN1; SMN2RXFP1 | |
| Hydrochloric Acid SCHEMBL7019827 | 0.70 | LMNA (0.82) | LMNAMAPK1ADORA2BSMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984413-A | ANTILIPEMIC, ANTICHOLESTEROLEMIC; PERIPHERAL AND VASOLIDATIVE EFFECT | L. MERCKLE KG (DT) | 1976-10-05 | — | — | US | disclosed |