Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 7/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824795 | 0.86 | ADAMTS4 (0.52) | PDCD1CD274ALDH1A1TDP1ADAMTS4 | |
| SCHEMBL11827041 | 0.85 | PDCD1 (0.43) | PDCD1CD274ALDH1A1TDP1ADAMTS4 | |
| SCHEMBL11837906 | 0.80 | ALDH1A1 (0.45) | PDCD1CD274ALDH1A1TDP1 | |
| SCHEMBL11830281 | 0.80 | CD274 (0.43) | PDCD1CD274MEN1KMT2APTGS2 | |
| SCHEMBL11834506 | 0.80 | CSNK2A1 (0.50) | CD274 | |
| SCHEMBL11846449 | 0.79 | ALDH1A1 (0.46) | PDCD1CD274ALDH1A1TDP1APP | |
| SCHEMBL9266029 | 0.78 | ALDH1A1 (0.49) | PDCD1CD274ALDH1A1TDP1 | |
| SCHEMBL11826299 | 0.78 | ALDH1A1 (0.45) | PDCD1CD274ALDH1A1TDP1 | |
| SCHEMBL3905288 | 0.77 | ALDH1A1 (0.58) | PDCD1CD274ALDH1A1TDP1 | |
| SCHEMBL11829977 | 0.77 | ALDH1A1 (0.44) | PDCD1CD274ALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |