Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11825216 | 0.92 | MEN1 (0.50) | MEN1KMT2AALOX15ALDH1A1TSHR | |
| SCHEMBL11824584 | 0.86 | ALOX15 (0.67) | MEN1KMT2AALOX15ALDH1A1TSHR | |
| SCHEMBL11822073 | 0.86 | MEN1 (0.51) | MEN1KMT2AALOX15ALDH1A1TSHR | |
| SCHEMBL11822825 | 0.86 | MEN1 (0.51) | MEN1KMT2AALOX15ALDH1A1TSHR | |
| SCHEMBL11819432 | 0.84 | MEN1 (0.49) | MEN1KMT2AALOX15ALDH1A1TSHR | |
| SCHEMBL9684571 | 0.82 | ADORA3 (0.49) | MEN1KMT2AALOX15ALDH1A1TSHR | |
| SCHEMBL11821165 | 0.81 | KMT2A (0.55) | MEN1KMT2AALOX15ALDH1A1TSHR | |
| SCHEMBL11828210 | 0.81 | ALDH1A1 (0.40) | ALDH1A1ADORA3JAK2JAK3HSP90AA1 | |
| SCHEMBL12929334 | 0.78 | ALDH1A1 (0.59) | MEN1KMT2AALOX15ALDH1A1TSHR | |
| SCHEMBL11873704 | 0.74 | ADORA3 (0.44) | MEN1KMT2AALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975384-A | ANTITHROMBOTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |