SCHEMBL11825751

SCHEMBL11825751

O=C(c1ccccc1)N(C(=O)N(C(=O)c1ccccc1)S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.62
APOBEC3G Q9HC16 1/20 0.45
KMT2A Q03164 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KAT6A Q92794 1/20 0.41
HSP90AA1 P07900 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MCOLN3 Q8TDD5 1/20 0.40
MEN1 O00255 1/20 0.40
TAS2R14 Q9NYV8 1/20 0.40
LIMK2 P53671 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11828717 0.92 HSD11B1 (0.67) HSD11B1APOBEC3GKMT2AL3MBTL1KAT6A
SCHEMBL23733154 0.89 HSD11B1 (0.62) HSD11B1APOBEC3GKMT2AL3MBTL1KAT6A
SCHEMBL23733161 0.85 HSD11B1 (0.59) HSD11B1APOBEC3GKMT2AL3MBTL1KAT6A
SCHEMBL11836506 0.80 HSD11B1 (0.53) HSD11B1KMT2AL3MBTL1ALDH1A1MEN1
SCHEMBL23733152 0.79 HSD11B1 (0.55) HSD11B1KMT2AL3MBTL1HSP90AA1ALDH1A1
SCHEMBL1925447 0.78 HSD11B1 (0.65) HSD11B1APOBEC3GKMT2AL3MBTL1KAT6A
SCHEMBL23733150 0.77 HSD11B1 (0.50) HSD11B1KMT2AL3MBTL1HSP90AA1ALDH1A1
SCHEMBL11832256 0.77 HSD11B1 (0.52) HSD11B1KMT2AL3MBTL1ALDH1A1CYP2C19
SCHEMBL6275528 0.77 APOBEC3G (0.54) HSD11B1APOBEC3GKMT2AALDH1A1MEN1
SCHEMBL11524385 0.77 HSD11B1 (0.62) HSD11B1APOBEC3GKMT2AL3MBTL1KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3948795-A Method of low-temperature activation of peroxides TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1976-04-06 US disclosed