Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733154 | 0.84 | HSD11B1 (0.62) | HSD11B1MAPTSMN1; SMN2HSP90AA1KMT2A | |
| SCHEMBL23733152 | 0.84 | HSD11B1 (0.55) | HSD11B1MAPTHSP90AA1KMT2AALDH1A1 | |
| SCHEMBL23733149 | 0.84 | ELANE (0.44) | HSD11B1MAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL23733161 | 0.81 | HSD11B1 (0.59) | HSD11B1MAPTSMN1; SMN2HSP90AA1KMT2A | |
| SCHEMBL11828717 | 0.81 | HSD11B1 (0.67) | HSD11B1MAPTSMN1; SMN2HSP90AA1KMT2A | |
| SCHEMBL11825751 | 0.77 | HSD11B1 (0.62) | HSD11B1MAPTSMN1; SMN2HSP90AA1KMT2A | |
| SCHEMBL11836506 | 0.70 | HSD11B1 (0.53) | HSD11B1MAPTKMT2AALDH1A1TDP1 | |
| SCHEMBL1925447 | 0.69 | HSD11B1 (0.65) | HSD11B1MAPTSMN1; SMN2HSP90AA1KMT2A | |
| SCHEMBL23733156 | 0.68 | TSHR (0.43) | HSD11B1MAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11832256 | 0.67 | HSD11B1 (0.52) | HSD11B1MAPTSMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | PYGL, HMOX2, MB | HSD11B1 602/4885MAPT 1259/4885SMN1; SMN2 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.