Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733154 | 0.93 | HSD11B1 (0.62) | HSD11B1APOBEC3GKMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL11828717 | 0.89 | HSD11B1 (0.67) | HSD11B1APOBEC3GKMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL11825751 | 0.85 | HSD11B1 (0.62) | HSD11B1APOBEC3GKMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL23733152 | 0.82 | HSD11B1 (0.55) | HSD11B1KMT2AL3MBTL1HSP90AA1TAS2R14 | |
| SCHEMBL23733150 | 0.81 | HSD11B1 (0.50) | HSD11B1KMT2AL3MBTL1HSP90AA1LIMK2 | |
| SCHEMBL23733159 | 0.80 | HSD11B1 (0.47) | HSD11B1KMT2AL3MBTL1ALDH1A1TSHR | |
| SCHEMBL11836506 | 0.77 | HSD11B1 (0.53) | HSD11B1KMT2AL3MBTL1MEN1TAS2R14 | |
| SCHEMBL1925447 | 0.76 | HSD11B1 (0.65) | HSD11B1APOBEC3GKMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL11832256 | 0.74 | HSD11B1 (0.52) | HSD11B1KMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL6275528 | 0.74 | APOBEC3G (0.54) | HSD11B1APOBEC3GKMT2AMEN1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | PYGL, HMOX2, MB | HSD11B1 602/4885APOBEC3G 3600/4885KMT2A 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.