Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733154 | 0.85 | HSD11B1 (0.62) | HSD11B1TSHRL3MBTL1HSP90AA1ALDH1A1 | |
| SCHEMBL23733156 | 0.84 | TSHR (0.43) | HSD11B1TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL23733150 | 0.84 | HSD11B1 (0.50) | HSD11B1L3MBTL1HSP90AA1ALDH1A1GAA | |
| SCHEMBL23733161 | 0.82 | HSD11B1 (0.59) | HSD11B1TSHRL3MBTL1HSP90AA1ALDH1A1 | |
| SCHEMBL11828717 | 0.82 | HSD11B1 (0.67) | HSD11B1TSHRL3MBTL1HSP90AA1ALDH1A1 | |
| SCHEMBL11825751 | 0.79 | HSD11B1 (0.62) | HSD11B1TSHRL3MBTL1HSP90AA1ALDH1A1 | |
| SCHEMBL26680105 | 0.72 | HSD11B1 (1.00) | HSD11B1L3MBTL1HSP90AA1ALDH1A1KDM4E | |
| SCHEMBL11836506 | 0.71 | HSD11B1 (0.53) | HSD11B1L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL27664717 | 0.71 | TSHR (0.46) | HSD11B1TSHRL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL23733149 | 0.70 | ELANE (0.44) | HSD11B1L3MBTL1ALDH1A1PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | PYGL, HMOX2, MB | HSD11B1 602/4885TSHR 4002/4885L3MBTL1 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.