Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | P4HB | P07237 | 2/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.38 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816193 | 0.96 | KMT2A (0.44) | KMT2AMEN1HTTCA12CA9 | |
| SCHEMBL11815605 | 0.86 | CA12 (0.46) | KMT2AMEN1CA12CA9CA2 | |
| SCHEMBL11820801 | 0.85 | NPC1 (0.45) | KMT2AMEN1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL11815261 | 0.84 | CNR2 (0.46) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL11819494 | 0.83 | CNR2 (0.47) | HTTCA12CA9CA2RAB9A | |
| SCHEMBL11816911 | 0.81 | CA12 (0.47) | KMT2AMEN1HTTCA12CA9 | |
| SCHEMBL11819309 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1HTT | |
| SCHEMBL11821805 | 0.81 | KMT2A (0.45) | KMT2AMEN1HTTCA12CA9 | |
| SCHEMBL11825369 | 0.81 | KMT2A (0.45) | KMT2AMEN1HTTCA12CA9 | |
| SCHEMBL11818861 | 0.81 | KMT2A (0.45) | KMT2AMEN1HTTCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |