Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | CPA1 | P15085 | 3/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834777 | 0.81 | MMP12 (0.48) | HTTMMEACECPA1ACE2 | |
| SCHEMBL11835616 | 0.79 | MEN1 (0.58) | KMT2AMEN1ALDH1A1SMYD3SMN1; SMN2 | |
| SCHEMBL11828803 | 0.79 | SRR (0.43) | MMEACECPA1ACE2 | |
| SCHEMBL11832270 | 0.78 | SRR (0.46) | HTTMMEACECPA1ACE2 | |
| SCHEMBL11826818 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL11827301 | 0.74 | SRR (0.45) | ALDH1A1MME | |
| SCHEMBL11828575 | 0.74 | SMYD3 (0.50) | KMT2AMEN1ALDH1A1SMYD3SMN1; SMN2 | |
| SCHEMBL11827473 | 0.74 | NAAA (0.52) | KMT2AMEN1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL11835980 | 0.74 | MEN1 (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11821169 | 0.73 | PPARA (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |