Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823532 | 0.92 | ESRRB (0.44) | MC4RRAD52LMNAMAPTTSHR | |
| SCHEMBL11850544 | 0.86 | MC4R (0.47) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11463532 | 0.85 | MC4R (0.47) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11834735 | 0.84 | MC4R (0.46) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11830029 | 0.82 | ALDH1A1 (0.50) | MAPK1LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL11847768 | 0.82 | MC4R (0.46) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11605905 | 0.81 | HTR1A (0.52) | LMNAMAPTTSHRALDH1A1RAB9A | |
| SCHEMBL11848250 | 0.81 | MC4R (0.48) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11856236 | 0.80 | HTR1A (0.52) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11611096 | 0.80 | SIGMAR1 (0.46) | LMNAALDH1A1NPC1RAB9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |