Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850544 | 0.88 | MC4R (0.47) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11479693 | 0.86 | ALDH1A1 (0.51) | MAPK1LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL11828024 | 0.85 | MC4R (0.46) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11471644 | 0.85 | MAPT (0.56) | MAPK1LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL11848250 | 0.82 | MC4R (0.48) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11476239 | 0.81 | HTR1A (0.53) | LMNAALDH1A1ALOX15HSD17B10POLB | |
| SCHEMBL11856236 | 0.81 | HTR1A (0.52) | MC4RRAD52MAPK1LMNAMAPT | |
| SCHEMBL11833966 | 0.80 | MC4R (0.47) | MC4RRAD52MAPK1USP2ALDH1A1 | |
| SCHEMBL11469451 | 0.79 | KMT2A (0.48) | ALDH1A1HTR2AMEN1KMT2A | |
| SCHEMBL11823532 | 0.78 | ESRRB (0.44) | MC4RRAD52LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235914-A | ANTIPSYCHOTIC, HYPOTENSIVE, DEPRESSANTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-11-25 | — | — | US | disclosed |