Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818098 | 0.83 | NR4A2 (0.44) | NR4A2MRGPRX4SRD5A2MEN1KMT2A | |
| SCHEMBL11671597 | 0.74 | NR4A2 (0.44) | NR4A2MRGPRX4EPHX1MEN1KMT2A | |
| SCHEMBL11810283 | 0.74 | NR4A2 (0.49) | NR4A2MRGPRX4SRD5A2MAOB | |
| SCHEMBL11817595 | 0.73 | POLB (0.49) | NR4A2MRGPRX4SRD5A2PRKCAPRKCD | |
| SCHEMBL11671988 | 0.73 | P2RY14 (0.41) | NR4A2EPHX1P2RY14MEN1KMT2A | |
| SCHEMBL11816786 | 0.72 | TDP1 (0.45) | SRD5A2P2RY14MEN1KMT2AMAPT | |
| SCHEMBL11816991 | 0.70 | MRGPRX4 (0.46) | NR4A2MRGPRX4MEN1KMT2A | |
| SCHEMBL11816615 | 0.70 | LMNA (0.51) | NR4A2MEN1KMT2AMAPT | |
| SCHEMBL19649588 | 0.69 | HTR2A (0.53) | EPHX1MAOBMEN1KMT2AMAPT | |
| SCHEMBL11818420 | 0.69 | TAS2R14 (0.43) | MRGPRX4MEN1KMT2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |