Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.40 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828037 | 0.82 | KMT2A (0.51) | KMT2AMMEKDM4E | |
| SCHEMBL9890641 | 0.80 | CXCL8 (0.57) | DPP4CXCL8AKR1B10UGT1A9TRPA1 | |
| SCHEMBL11828626 | 0.79 | MME (0.62) | MMECTSA | |
| SCHEMBL11827363 | 0.79 | TSHR (0.48) | KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11827466 | 0.79 | CHRM1 (0.48) | KMT2AMMEPTGS2CTSA | |
| SCHEMBL11837145 | 0.77 | DPP4 (0.40) | DPP4KMT2AMMECXCL8CTSA | |
| SCHEMBL11836998 | 0.76 | PPARG (0.48) | DPP4KMT2APTGS2AKR1B1KDM4E | |
| SCHEMBL11828598 | 0.73 | MME (0.51) | MMEPTGS1CTSA | |
| SCHEMBL6465862 | 0.72 | CPA3 (0.60) | TRPA1PTGS1AKR1B1 | |
| SCHEMBL11833616 | 0.72 | DPP4 (0.46) | DPP4KMT2ACXCL8AKR1B10UGT1A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |