Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830975 | 0.91 | TP53 (0.41) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11826484 | 0.85 | ALDH1A1 (0.43) | TP53ALDH1A1MAPTKCNH2 | |
| SCHEMBL10993844 | 0.84 | ALDH1A1 (0.41) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11819574 | 0.81 | CRHBP (0.48) | NPC1RAB9APAX8ALDH1A1LMNA | |
| SCHEMBL9971662 | 0.80 | ALDH1A1 (0.39) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11829272 | 0.78 | TP53 (0.40) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11836303 | 0.78 | NPC1 (0.38) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11821127 | 0.77 | KCNH2 (0.45) | NPC1RAB9ATP53ALDH1A1KCNH2 | |
| SCHEMBL11822816 | 0.77 | TP53 (0.45) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11834659 | 0.77 | ALDH1A1 (0.41) | TP53ALDH1A1MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974178-A | POLYESTER, POLYAMIDE, POLYACRYLONITRILE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-08-10 | — | — | US | disclosed |