Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828887 | 0.91 | NPC1 (0.40) | TP53KCNH2ALDH1A1NPC1JAK2 | |
| SCHEMBL11826484 | 0.88 | ALDH1A1 (0.43) | TP53KCNH2ALDH1A1GLATSHR | |
| SCHEMBL11829272 | 0.87 | TP53 (0.40) | TP53ALDH1A1GLATSHRTRPM8 | |
| SCHEMBL11822816 | 0.85 | TP53 (0.45) | TP53ALDH1A1GLATSHRTRPM8 | |
| SCHEMBL11819574 | 0.84 | CRHBP (0.48) | ALDH1A1GLATSHRSMN1; SMN2NPC1 | |
| SCHEMBL11821127 | 0.80 | KCNH2 (0.45) | TP53KCNH2ALDH1A1GLATSHR | |
| SCHEMBL11834659 | 0.79 | ALDH1A1 (0.41) | TP53KCNH2ALDH1A1GLATSHR | |
| SCHEMBL9971662 | 0.77 | ALDH1A1 (0.39) | TP53KCNH2ALDH1A1GLATSHR | |
| SCHEMBL10993844 | 0.75 | ALDH1A1 (0.41) | TP53KCNH2ALDH1A1NPC1JAK2 | |
| SCHEMBL11825761 | 0.75 | TP53 (0.43) | TP53ALDH1A1GLATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974178-A | POLYESTER, POLYAMIDE, POLYACRYLONITRILE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-08-10 | — | — | US | disclosed |