Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089845 | 0.96 | KCNH2 (0.37) | ALDH1A1HPGDBCHECNR2TSHR | |
| SCHEMBL14673301 | 0.86 | CNR2 (0.44) | ALDH1A1BCHECNR2TSHRMAPK1 | |
| SCHEMBL6958576 | 0.86 | OPRM1 (0.44) | BCHE | |
| SCHEMBL6551944 | 0.84 | ALDH1A1 (0.40) | ALDH1A1CNR2TSHRMAPK1L3MBTL1 | |
| SCHEMBL18597669 | 0.81 | ALDH1A1 (0.35) | ALDH1A1BCHECNR2TSHRMAPK1 | |
| SCHEMBL6637466 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDBCHETSHRMAPK1 | |
| SCHEMBL102928 | 0.78 | TSHR (0.42) | ALDH1A1BCHECNR2TSHRMAPK1 | |
| SCHEMBL20367069 | 0.78 | MAPT (0.50) | ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL10711575 | 0.77 | TSHR (0.50) | ALDH1A1CNR2TSHRMAPK1MAOB | |
| SCHEMBL19064329 | 0.77 | TSHR (0.50) | ALDH1A1CNR2TSHRMAPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519499-B1 | PESTICIDAL ARYLPYRROLIDINES | BAYER IP GMBH (DE) | 2013-09-18 | — | — | EP | claimed |
| US-8536201-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-17 | — | — | US | claimed |
| CN-102844299-A | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG | 2012-12-26 | — | — | CN | claimed |
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-20 | — | — | US | claimed |
| EP-0789699-B1 | SPIRO[HETEROCYCLE-IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE]-4'-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1999-03-17 | — | — | EP | claimed |
| US-5777114-A | Spiro heterocycle-imidazo 1,2-a!indeno 1,2-e!pyrazine!-4'-ones, preparation thereof and drugs containing same | RHONE-POULENC RORER S.A. (FR) | 1998-07-07 | — | — | US | claimed |
| EP-0789699-A1 | SPIRO HETEROCYCLE-IMIDAZO(1,2-a]INDENO(1,2-e]PYRAZINE]-4'-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-08-20 | — | — | EP | claimed |
| WO-1996014318-A1 | SPIRO[HETEROCYCLE-IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE]-4'-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1996-05-17 | — | — | WO | claimed |
| EP-3095780-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2016-11-23 | — | — | EP | disclosed |
| CN-102844299-B | Desinsection aryl-pyrrolidine alkane | BAYER CROPSCIENCE AG (DE) | 2016-03-30 | — | — | CN | disclosed |
| US-9271499-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9266830-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| CN-103483235-B | The aryl pyrrolidines of desinsection | BAYER LANDWIRTSCHAFTLICHE KULTURPFLANZEN SCIENCE AG (DE) | 2015-09-09 | — | — | CN | disclosed |
| US-20150152086-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| EP-0514274-A1 | Perhydroisoindole derivatives and their preparation | Aventis Pharma S.A. (FR) | 1992-11-19 | — | — | EP | disclosed |
| EP-0514273-A1 | New derivatives of perhydroisoindole, their preparation and pharmaceutical compositions containing them | Aventis Pharma S.A. (FR) | 1992-11-19 | — | — | EP | disclosed |
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |
| EP-0430771-A1 | Isoindolone derivatives, their preparation and their use as intermediates for the preparation of substance P antagonists | RHONE-POULENC SANTE (FR) | 1991-06-05 | — | — | EP | disclosed |
| EP-0429366-A1 | Isoindolone derivatives, their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1991-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152086-A1 | Insecticidal Aryl Pyrrolidines | DDT, ITPR3, CYP51A1 | ALDH1A1 261/4885HPGD 2188/4885BCHE 823/4885 |
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | DDT, CYP4X1, CHRM2 | ALDH1A1 1542/4885HPGD 2141/4885BCHE 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.