Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610203 | 0.85 | RAD52 (0.55) | RAD52POLBHTR6KDM4EALDH1A1 | |
| SCHEMBL11755867 | 0.77 | MAPT (0.65) | HTR6KDM4EALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11828278 | 0.75 | ALDH1A1 (0.63) | POLBHTR6KDM4EALDH1A1MAPT | |
| SCHEMBL11832005 | 0.75 | KDM4E (0.44) | RAD52KDM4EALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11828036 | 0.74 | KDM4E (0.43) | RAD52KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL24900472 | 0.72 | KDM4E (0.64) | RAD52KDM4EALDH1A1MAPTHTT | |
| SCHEMBL30957519 | 0.72 | KDM4E (0.64) | RAD52KDM4EALDH1A1MAPTHTT | |
| SCHEMBL2263609 | 0.72 | HTR6 (0.49) | RAD52POLBHTR6KDM4EALDH1A1 | |
| SCHEMBL4009576 | 0.71 | KDM4E (0.43) | RAD52POLBKDM4EALDH1A1MAPT | |
| SCHEMBL7636415 | 0.71 | POLB (0.43) | RAD52POLBKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032520-A1 | Indol-5-yl sulfonamide derivatives, their preparation and their use 5-ht-6 as modulators | LABORATORIOS DEL DR. ESTEVE S.A (ES) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032520-A1 | Indol-5-yl sulfonamide derivatives, their preparation and their use 5-ht-6 as modulators | HTR6, HTR5A, TPH1 | RAD52 4579/4885POLB 4655/4885HTR6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.