Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830651 | 0.87 | GABRA3 (0.42) | GABRA1GABRA5GABRA2GABRG2GABRB3 | |
| SCHEMBL11824108 | 0.86 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRG2GABRB3 | |
| SCHEMBL11832829 | 0.86 | OPRK1 (0.45) | GABRA1GABRA5GABRA2GABRG2GABRB3 | |
| SCHEMBL11823482 | 0.86 | GABRA1 (0.45) | GABRA1GABRA5GABRA2GABRG2GABRB3 | |
| SCHEMBL11829527 | 0.85 | CHRM1 (0.47) | GABRA1GABRA5GABRA2GABRG2GABRB3 | |
| SCHEMBL11827831 | 0.84 | GABRA1 (0.48) | GABRA1GABRA5GABRA2GABRG2GABRB3 | |
| SCHEMBL11822656 | 0.84 | CHRM1 (0.47) | GABRA1GABRA5GABRA2GABRG2GABRB3 | |
| SCHEMBL11829616 | 0.83 | GABRA1 (0.36) | GABRA1GABRA5GABRA2GABRG2GABRB3 | |
| SCHEMBL11829663 | 0.82 | MEN1 (0.35) | POLB | |
| SCHEMBL11610755 | 0.82 | HTT (0.38) | GABRA1GABRA5GABRA2GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933794-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |