Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360957 | 0.84 | LCK (0.59) | LCKFYNMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL11833701 | 0.80 | HPGD (0.55) | CNR1CNR2TSHRCYP1A2CYP2C9 | |
| SCHEMBL6256749 | 0.80 | ALDH1A1 (0.58) | HSD17B10ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12682412 | 0.78 | LCK (0.62) | LCKFYNTSHRHSD17B10ALDH1A1 | |
| SCHEMBL1933162 | 0.77 | RAB9A (0.53) | CNR1CNR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24353844 | 0.77 | POLB (0.44) | MTNR1AMTNR1BCNR1CNR2RAB9A | |
| SCHEMBL17602018 | 0.76 | LCK (0.65) | LCKFYNTSHRHSD17B10ALDH1A1 | |
| SCHEMBL8434080 | 0.76 | CTSD (0.61) | TSHRHSD17B10RAB9AMEN1MAPT | |
| SCHEMBL2332823 | 0.75 | LCK (0.59) | LCKFYNTSHRHSD17B10ALDH1A1 | |
| SCHEMBL15651310 | 0.75 | KDM4E (0.40) | CNR1CNR2ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985889-A | 1,3-DIHYDROSPIRO(ISOBENZOFURAN); ANALGETIC AGENTS | AMERICAN HOECHST CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |
| US-3962259-A | TRANQUILIZERS, ANALGETIC AGENTS | AMERICAN HOECHST CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |