Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | HRH2 | P25021 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822106 | 0.91 | MAPT (0.50) | CYP2D6CNR2DRD3HTR6PSEN1 | |
| SCHEMBL29907915 | 0.86 | CYP2D6 (0.74) | CYP2D6CNR2DRD3CHRM2HTR1A | |
| SCHEMBL541688 | 0.86 | CYP2D6 (0.74) | CYP2D6CNR2DRD3CHRM2HTR1A | |
| SCHEMBL11510880 | 0.84 | MPO (0.48) | CYP2D6CNR2MPOXDHPSEN1 | |
| SCHEMBL1923371 | 0.84 | PSEN1 (0.63) | CNR2PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL11824254 | 0.83 | MPO (0.49) | CYP2D6HTR1ADRD2MPOXDH | |
| SCHEMBL11754129 | 0.83 | KDM4E (0.61) | CYP2D6CNR2DRD3CHRM2HTR1A | |
| SCHEMBL6219453 | 0.82 | CYP2D6 (0.65) | CYP2D6CNR2DRD3CHRM2HTR1A | |
| SCHEMBL1921889 | 0.80 | ALDH1A1 (0.60) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL541651 | 0.80 | PTGER4 (0.64) | CYP2D6CNR2DRD3CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3988208-A | FOR GLUCOSE | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-10-26 | — | — | US | disclosed |
| US-3975398-A | INDICATOR FOR DETERMINATION OF GLUCOSE | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-08-17 | — | — | US | disclosed |