SCHEMBL1923371

SCHEMBL1923371

CCCCn1c2ccccc2c2cc(Cl)ccc21

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PSEN1 P49768 5/20 0.63
▸ PSEN2 P49810 5/20 0.63
▸ APH1B Q8WW43 5/20 0.63
▸ NCSTN Q92542 5/20 0.63
▸ APH1A Q96BI3 5/20 0.63
▸ PSENEN Q9NZ42 5/20 0.63
▸ PGR P06401 3/20 0.56
▸ RORA P35398 3/20 0.56
▸ RORC P51449 3/20 0.56
▸ RORB Q92753 3/20 0.56
▸ CNR2 P34972 6/20 0.54
▸ ALDH1A1 P00352 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ TSHR P16473 1/20 0.51
▸ ALOX12 P18054 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921483 0.92 PSEN1 (0.67) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1921889 0.90 ALDH1A1 (0.60) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL8086740 0.88 RORA (0.55) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29543602 0.88 RORA (0.55) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1335135 0.85 PGR (0.73) PGRRORARORCRORBCNR2
SCHEMBL29531665 0.85 PGR (0.73) PGRRORARORCRORBCNR2
SCHEMBL11834370 0.84 CYP2D6 (0.59) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1921288 0.83 MAPT (0.65) ALDH1A1KDM4EMAPTTSHRALOX12
SCHEMBL29643271 0.83 MAPT (0.65) ALDH1A1KDM4EMAPTTSHRALOX12
SCHEMBL8831384 0.83 PSEN1 (0.51) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2327739-B1 Novel triarylamine polymer, process for its production and its use TOSOH CORP (JP) 2014-05-07 — — EP disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 — — EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 — — EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 — — US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 — — US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 — — US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 — — EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 — — US disclosed
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