SCHEMBL1921889

SCHEMBL1921889

CCCn1c2ccccc2c2cc(Cl)ccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
HPGD P15428 2/20 0.60
PSEN1 P49768 4/20 0.55
PSEN2 P49810 4/20 0.55
APH1B Q8WW43 4/20 0.55
NCSTN Q92542 4/20 0.55
APH1A Q96BI3 4/20 0.55
PSENEN Q9NZ42 4/20 0.55
MAPT P10636 4/20 0.54
KDM4E B2RXH2 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
TSHR P16473 1/20 0.54
ALOX12 P18054 1/20 0.54
CNR2 P34972 3/20 0.51
TP53 P04637 2/20 0.51
TDP1 Q9NUW8 2/20 0.49
MEN1 O00255 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
HBB P68871 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921824 0.91 PSEN1 (0.57) ALDH1A1HPGDPSEN1PSEN2APH1B
SCHEMBL1923371 0.90 PSEN1 (0.63) ALDH1A1PSEN1PSEN2APH1BNCSTN
SCHEMBL29660662 0.88 ALDH1A1 (0.54) ALDH1A1HPGDMAPTTP53MEN1
SCHEMBL20291531 0.88 ALDH1A1 (0.54) ALDH1A1HPGDMAPTTP53MEN1
SCHEMBL1921288 0.86 MAPT (0.65) ALDH1A1HPGDMAPTKDM4EL3MBTL1
SCHEMBL29643271 0.86 MAPT (0.65) ALDH1A1HPGDMAPTKDM4EL3MBTL1
SCHEMBL153959 0.84 ALDH1A1 (0.62) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL30854944 0.84 ALDH1A1 (0.62) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL30012682 0.84 ALDH1A1 (0.62) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL17854676 0.83 HPGD (0.63) ALDH1A1HPGDMAPTKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2327739-B1 Novel triarylamine polymer, process for its production and its use TOSOH CORP (JP) 2014-05-07 EP disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed