Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707993 | 0.70 | GAK (0.44) | PTGDR2MCHR1CSNK1DCCNE2CCNA2 | |
| SCHEMBL14916129 | 0.68 | KHK (0.39) | PTGDR2MCHR1CSNK1DCCNE2CCNA2 | |
| SCHEMBL14916134 | 0.68 | KHK (0.37) | PTGDR2MCHR1CCNE2CCNA2CCNE1 | |
| SCHEMBL14916710 | 0.68 | FABP4 (0.43) | TDP1L3MBTL1IDO1DGAT1 | |
| SCHEMBL14916476 | 0.66 | ESR1 (0.41) | TDP1L3MBTL1IDO1DGAT1 | |
| SCHEMBL16529006 | 0.65 | GABRA2 (0.36) | PTGDR2 | |
| SCHEMBL28112248 | 0.65 | EGFR (0.40) | IRAK4CCRL2DGAT1 | |
| SCHEMBL23066230 | 0.63 | PTGDR2 (0.41) | PTGDR2CSNK1D | |
| SCHEMBL25647216 | 0.63 | PPARD (0.42) | PTGDR2L3MBTL1 | |
| SCHEMBL11866171 | 0.63 | ACHE (0.37) | PTGDR2TDP1L3MBTL1PDE10ARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933794-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |