Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822139 | 0.88 | HTR1A (0.51) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL11473465 | 0.84 | DRD2 (0.57) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| SCHEMBL11822130 | 0.81 | MAPK1 (0.43) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL11827955 | 0.78 | HTR2A (0.51) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL11837329 | 0.76 | HTR1A (0.62) | DRD2HTR1AHTR7 | |
| SCHEMBL11831658 | 0.76 | HTR1A (0.62) | DRD2HTR2AHTR1A | |
| SCHEMBL24322504 | 0.76 | SIGMAR1 (0.62) | DRD2HTR1AKCNH2CYP2D6 | |
| SCHEMBL11834735 | 0.76 | MC4R (0.46) | DRD2HTR2AHTR1A | |
| SCHEMBL11828024 | 0.76 | MC4R (0.46) | DRD2HTR2AHTR1A | |
| SCHEMBL6221057 | 0.76 | KCNH2 (0.62) | DRD2HTR1AHTR7KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |