Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | RAD52 | P43351 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841247 | 0.92 | KDM4E (0.68) | KDM4EALDH1A1MAPTRAB9AGAA | |
| SCHEMBL11838114 | 0.91 | KDM4E (0.67) | KDM4EALDH1A1MAPTRAB9AGAA | |
| SCHEMBL11632652 | 0.89 | NPSR1 (0.67) | KDM4EALDH1A1MAPTRAB9AGAA | |
| SCHEMBL11848412 | 0.88 | KDM4E (0.68) | KDM4EALDH1A1MAPTRAB9AGAA | |
| SCHEMBL28284669 | 0.87 | ALDH1A1 (1.00) | KDM4EALDH1A1MAPTRAB9AGAA | |
| SCHEMBL11632287 | 0.84 | HTR7 (0.70) | KDM4EALDH1A1MAPTGAARAD52 | |
| SCHEMBL11632801 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1MAPTRAB9AGAA | |
| SCHEMBL11803997 | 0.82 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPTRAB9AGAA | |
| SCHEMBL11623083 | 0.82 | HEXA (0.74) | KDM4EALDH1A1MAPTRAB9AGAA | |
| SCHEMBL6272682 | 0.81 | MAPT (0.73) | KDM4EALDH1A1MAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940397-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-02-24 | — | — | US | disclosed |