Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838114 | 0.96 | KDM4E (0.67) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11834897 | 0.92 | KDM4E (0.76) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11836334 | 0.89 | MEN1 (0.64) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11632652 | 0.87 | NPSR1 (0.67) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11632801 | 0.86 | KDM4E (0.60) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11807610 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL28284669 | 0.82 | ALDH1A1 (1.00) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11809050 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11632287 | 0.82 | HTR7 (0.70) | KDM4EALDH1A1GAAMAPTRAD52 | |
| SCHEMBL11801164 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1GAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940397-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-02-24 | — | — | US | disclosed |