Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | UBE2N | P61088 | 1/20 | 0.63 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834897 | 0.88 | KDM4E (0.76) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL11630456 | 0.85 | HTR1A (0.71) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL11841247 | 0.81 | KDM4E (0.68) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL11632652 | 0.81 | NPSR1 (0.67) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL11836334 | 0.81 | MEN1 (0.64) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL11838114 | 0.80 | KDM4E (0.67) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL11842208 | 0.80 | KDM4E (0.61) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL11830608 | 0.80 | KDM4E (0.59) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL11632587 | 0.80 | L3MBTL1 (0.50) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL11623083 | 0.79 | HEXA (0.74) | KDM4EMAPTLMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940397-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-02-24 | — | — | US | disclosed |