Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 12/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829891 | 0.87 | HRH2 (0.46) | L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11832023 | 0.86 | ALDH1A1 (0.44) | PDCD1CD274ALDH1A1TDP1 | |
| SCHEMBL11834253 | 0.83 | CSNK2A1 (0.46) | PDCD1CD274 | |
| SCHEMBL11829788 | 0.80 | PDCD1 (0.40) | PDCD1CD274ALDH1A1TDP1PPARG | |
| SCHEMBL11827662 | 0.78 | MMP12 (0.56) | L3MBTL1 | |
| SCHEMBL11826299 | 0.78 | ALDH1A1 (0.45) | PDCD1CD274ALDH1A1TDP1 | |
| SCHEMBL11823599 | 0.76 | MAPT (0.38) | ALDH1A1 | |
| SCHEMBL11829659 | 0.76 | MAPT (0.48) | L3MBTL1ALDH1A1 | |
| SCHEMBL11827539 | 0.75 | PTPN1 (0.42) | L3MBTL1ALDH1A1TDP1PPARG | |
| SCHEMBL27559990 | 0.75 | FFAR1 (0.53) | PDCD1CD274ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |