Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835155 | 0.87 | PDCD1 (0.42) | L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11829509 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TDP1ADAMTS4CYP1A2POLB | |
| SCHEMBL11829659 | 0.82 | MAPT (0.48) | L3MBTL1ALDH1A1TSHRGAAKDM4E | |
| SCHEMBL11824134 | 0.82 | MAOB (0.48) | ALDH1A1KDM4EMAPTPTPN1SMN1; SMN2 | |
| SCHEMBL11845170 | 0.81 | HRH2 (0.49) | HRH2HRH1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11827662 | 0.80 | MMP12 (0.56) | L3MBTL1TSHRGAAMAPTPTPN1 | |
| SCHEMBL11828776 | 0.79 | HRH2 (0.46) | HRH2HRH1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11842360 | 0.77 | HRH2 (0.50) | HRH2HRH1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11833045 | 0.76 | HRH2 (0.46) | HRH2HRH1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11837592 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1ADAMTS4CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |